Recombinant Antibody Production Service

Biologics International Corp (BIC) provides recombinant antibody production services. BIC has extensive expertise and research experience in the field of recombinant antibody production. We have established a solid platform offering the expression of a range of recombinant antibodies, including IgG, IgD, IgE, nanobody (VHH), scFv, di-scFv, Fab, F(ab'), chimeric antibody, Fc fusion protein and more. We are so confident in our antibody production services, we offer a no-success no-fee guarantee.

Expression System

We have CHO and HEK293 cells for recombinant antibody production in the mammalian system.

Key Features

What We Offer

The following full-length antibodies and fragments can be produced by BIC:

Antibody Fragment Introduction
scFv/di-scFv
scFv/di-scFv
  • scFv consisting of the VH and VL domains linked by a flexible peptide
  • Di-scFv is produced by connecting two scFv molecules through a short linker
  • It retains the complete activity and stability of the whole Ig molecule with higher assay sensitivity
Nanobody(VHH)
Nanobody(VHH)
  • Nanobody is the single variable domain of the antibodies heavy-chain
  • It has high affinity and specificity, whereas the immunogenicity is very low
  • It is the smallest naturally found antigen-binding region
 Fab/F(ab’)
Fab/F(ab’)
  • Fab is composed of one constant domain and one variable domain of each of the heavy and light chains (VH and CL)
  • It can stably combine with the antigen
Full-length Antibody Introduction
IgG/IgD/IgE
Ig
  • IgG antibody has four isotypes
  • You need to choose the light chain - κ & λ
  • We provide production of recombinant IgG, IgE and IgD
Chimeric
Chimeric
  • Chimeric antibody fuses variable domains from your antibody
  • It can be combined with any constant domain from a different species
  • It retains the original affinity and specificity of the parent
Fc fusion protein
Fc fusion protein
  • It is composed of the Fc domain of IgG linked to the protein of your interest
  • Fusion an active protein with Fc can extend in vivo half-life with better protein stability

Recombinant Antibody Production Service

service description

Customer provides Recombinant antibody production service Deliverables Timeline
Recombinant antibody sequences Gene synthesis Codon optimization
  • 4 ug gene in cloning vector
  • >90% purity antibody
  • Quantity as per customer requirements
  • QC report
7-9 weeks
Vector construction
Misc. Sub-cloning &
DNA max-prep
Antibody production Recombinant antibody expression
Antibody purification Protein A/G purification
QC SDS-PAGE & Western blot

Two options for recombinant antibody expression

recombinant antibody production

Contact Us

phone+1 (317) 703-0614
fax +1 (855) 427-1516
 For questions and/or a price quote, please inquire online or fill in a pre-order form.
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