Interleukin-10 (IL-10) family

The IL-10 superfamily is highly pleiotropic. Its members are linked together through genetic similarity and intron-exon gene structure. Significant commonality exists not only through shared

receptors but also through conserved signaling cascades. However, its members mediate diverse activities, including immune suppression, enhanced antibacterial and antiviral immunity, antitumor activity, and promotion of self-tolerance in autoimmune diseases.